반응 #56319

반응 방정식

2-Methoxyaniline

sodium carbonate

2-Bromomethyl-4-methyl-5-ethyl-1,3-dioxolane

→

N-(4-methyl-5-ethyl-1,3-dioxolan-2-ylmethyl)-2-methoxyaniline

반응 조건

후처리

1. 1
   기타equipped with a mechanical stirrer
2. 2
   온도thermometer and reflux condenser
3. 3
   온도the reaction mixture is heated
4. 4
   온도at reflux for a period of about 1 hour
5. 5
   여과After this time the reaction mixture is filtered
6. 6
   workup.ADDITIONadditional sodium carbonate (5 grams) is added to the filtrate
7. 7
   workup.DISTILLATIONThe mixture is then distilled under reduced pressure

실험 절차

2-Methoxyaniline (0.05 mole) and sodium carbonate (30 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2-Bromomethyl-4-methyl-5-ethyl-1,3-dioxolane (0.55 mole) is slowly added and the reaction mixture is heated at reflux for a period of about 1 hour. After this time the reaction mixture is filtered and additional sodium carbonate (5 grams) is added to the filtrate. The mixture is then distilled under reduced pressure to yield the desired product N-(4-methyl-5-ethyl-1,3-dioxolan-2-ylmethyl)-2-methoxyaniline.

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