반응 #5610

반응 방정식

5-benzyloxy-2-vinyl-4-pyridone

pyrrolidine

→

5-benzyloxy-2-[2-(1-pyrrolidinyl)ethyl]4-pyridone

용매

tetrahydrofuran

diisopropyl ether

반응 조건

후처리

1. 1
   온도was heated
2. 2
   온도refluxed for an hour
3. 3
   온도The mixture was cooled
4. 4
   여과the resulting precipitate was collected by filtration
5. 5
   세척washed with diisopropyl ether
6. 6
   기타air-dried at ambient temperature

실험 절차

A mixture of 5-benzyloxy-2-vinyl-4-pyridone (2.90 g) and pyrrolidine (5.33 ml) was heated and refluxed for an hour. The mixture was cooled and diluted with tetrahydrofuran (20 ml) and diisopropyl ether (80 ml). After being stirred for an hour at ambient temperature, the resulting precipitate was collected by filtration, washed with diisopropyl ether and air-dried at ambient temperature to give 5-benzyloxy-2-[2-(1-pyrrolidinyl)ethyl]4-pyridone (3.79 g).

출처