반응 #56042

반응 방정식

5-cyano-6-formyl-2-[(1-methylpropyl)amino]-3-pyridine-carboxylic acid, ethyl ester

hydrazine hydrate

→

5-Cyano-6-methylidene-hydrazino-2-[(1-methylpropyl)amino]-3-pyridine-carboxylic acid, ethyl ester

용매

methanol

반응 조건

후처리

1. 1
   workup.WAITAfter standing over night
2. 2
   기타the title compound precipitates

실험 절차

2.8 g of 5-cyano-6-formyl-2-[(1-methylpropyl)amino]-3-pyridine-carboxylic acid, ethyl ester (0.01 mol) are dissolved in 10 ml of methanol and 1 g of hydrazine hydrate is added with stirring. After standing over night the title compound precipitates. Yield 2.1 g (73%); m.p. 120°-121° C. (methanol).

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