반응 #55959

반응 방정식

2-Bromo-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene

sodium acetate

formamide

acetic anhydride

→

2-Cyano-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene

수율 96.0%

용매

n-butyl acetate

반응 조건

후처리

1. 1
   온도heated
2. 2
   온도The temperature is maintained for 5 hours after which time the reaction
3. 3
   온도The mixture is cooled to room temperature
4. 4
   기타The precipitate is collected
5. 5
   세척washed with petroleum-ether (100 parts)
6. 6
   기타dried

실험 절차

2-Bromo-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene (2.4 parts), copper (II) chloride (0.67 parts), anhydrous sodium acetate (1.2 parts), formamide (1.8 parts), acetic anhydride (2.0 parts) and n-butyl acetate (44 parts) are mixed together and heated, with stirring, to 110° C. during 15 minutes. The temperature is maintained for 5 hours after which time the reaction is complete. The mixture is cooled to room temperature and poured into petroleum-ether (boiling range 60-80°) (400 parts). The precipitate is collected, washed with petroleum-ether (100 parts) and dried. 2-Cyano-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene is obtained in 96% yield.

출처