반응 #55955

반응 방정식

2-Bromo-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino) azobenzene

sodium acetate

formamide

acetic anhydride

→

2-Cyano-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene

수율 88.0%

용매

n-butyl acetate

반응 조건

후처리

1. 1
   온도heated
2. 2
   온도The temperature is maintained at 110° for 30 to 50 minutes
3. 3
   기타when a solid is suddenly precipitated from the reaction mixture
4. 4
   기타completion of the reaction
5. 5
   온도to cool to room temperature
6. 6
   기타the product is collected
7. 7
   세척washed with ethanol
8. 8
   기타to remove residual n-butyl acetate
9. 9
   기타dried

실험 절차

2-Bromo-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino) azobenzene (479 parts), copper (I) iodide (19 parts), anhydrous sodium acetate (246 parts), formamide (180 parts), acetic anhydride (408 parts) and n-butyl acetate (2190 parts) are mixed together and heated, with stirring, to 110° C. during 15 minutes. The temperature is maintained at 110° for 30 to 50 minutes, when a solid is suddenly precipitated from the reaction mixture, indicating completion of the reaction. The mixture is allowed to cool to room temperature and the product is collected, washed with ethanol to remove residual n-butyl acetate and dried. 2-Cyano-4,6-dinitro-2'-acetylamino-4'-(N,N-diethylamino)azobenzene is obtained in 88% yield and requires no purification.

출처