반응 #5592

ord-0c853584f40147fcac7748a5dc4bc09f

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    여과The light tan solid was filtered
  2. 2
    세척washed well with ethyl ether
  3. 3
    기타The solvent and triethylamine were removed

실험 절차

Following the procedure of Example 3, a solution of acryloyl chloride (4.05 ml, 0.05 mole) in ethyl ether (50 ml) was added dropwise to a cold 5° C. mixture of triethylamine (15.3 ml, 0.11 mole) and norpinylamine (6.96; g, 0.05 mole) in ethyl ether (400 ml). The reaction was allowed to warm to room temperature and stirred for 72 hours. The light tan solid was filtered and washed well with ethyl ether. The solvent and triethylamine were removed, leaving the title product as an oily solid. The structure was confirmed by NMR.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05244899uspto-grants-1993_09