반응 #55887
ord-1a45026a3a0b4759a631b4eaeb0394b6
반응 방정식
L-proline tert-butyl ester
3-acetylthio-2-methylpropanoyl chloride
4-methoxy-L-proline tert-butyl ester
4-methoxy-L-proline
3-acetylthiopropanoyl chloride
L-proline
→
4,5-dihydro-1-(3-mercapto-1-oxopropyl)-4-methoxy-1H-pyrrole-2-carboxylic acid
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
By substituting 4-methoxy-L-proline tert-butyl ester [prepared from 4-methoxy-L-proline by the procedure described in J. Am. Chem. Soc., 82, 3359 (1960) for L-proline] for the L-proline tert-butyl ester and 3-acetylthiopropanoyl chloride for the 3-acetylthio-2-methylpropanoyl chloride in the procedure of Example 1, and then submitting the product to the procedure of Example 2, 4,5-dihydro-1-(3-mercapto-1-oxopropyl)-4-methoxy-1H-pyrrole-2-carboxylic acid is obtained.