반응 #55782

반응 방정식

2-chloromethylpyrimidine

phthalimidoethanethiol

methylamine

2-[(2-aminoethyl)thiomethyl]-pyrimidine

→

N-cyano-N'-methyl-N"-[2-(2pyrimidylmethylthio)ethyl]-guanidine

반응 조건

실험 절차

Reacting 2-chloromethylpyrimidine with phthalimidoethanethiol by the procedure of Example 1(i)(b) and then reacting the resulting 2-[(2-aminoethyl)thiomethyl]-pyrimidine with dimethyl-N-cyanoimidodithiocarbonate and methylamine by the procedure of Example 3(d) gives N-cyano-N'-methyl-N"-[2-(2pyrimidylmethylthio)ethyl]-guanidine.

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