반응 #55703

반응 방정식

caprolactim methyl ether

benzyl cyanide

1,5-diazabicyclo [5.4.0]undec-5-ene

→

title compound

수율 41.7%

2-(α-cyanobenzylidene)perhydroazepine

수율 41.7%

반응 조건

후처리

1. 1
   기타distil off any excess benzyl cyanide under a high vacuum, and rub down the thus-produced residue with a little methyl alcohol
2. 2
   여과before filtering

실험 절차

Stir 8.1 g of caprolactim methyl ether and 5.0 g of benzyl cyanide with 0.6 g of 1,5-diazabicyclo [5.4.0]undec-5-ene under nitrogen for 48 hours at 130°; distil off any excess benzyl cyanide under a high vacuum, and rub down the thus-produced residue with a little methyl alcohol before filtering to obtain 3.78 g of the title compound. Recrystallize from methyl alcohol to obtain a purer product, MP 108° to 113°.

출처