반응 #55613

반응 방정식

2,5-dimethyl-4-(methylthio)phenol

dimethylcarbamoyl chloride

→

4-dimethylcarbamoyloxy-2,5-dimethylphenyl methyl sulphide

용매

pyridine

반응 조건

후처리

1. 1
   workup.ADDITIONAddition to excess of ice-cold dilute hydrochloric acid
2. 2
   기타gave an oil
3. 3
   추출The oil product was extracted into ether
4. 4
   세척washed three times with cold dilute sodium hydroxide
5. 5
   건조once with water, dried
6. 6
   기타the ether removed by evaporation

실험 절차

A mixture of 25.2 g 2,5-dimethyl-4-(methylthio)phenol and 20.3 ml dimethylcarbamoyl chloride in 70 ml dry pyridine was heated for 24 hours at 100° C. Addition to excess of ice-cold dilute hydrochloric acid gave an oil. The oil product was extracted into ether and washed three times with cold dilute sodium hydroxide and once with water, dried, and the ether removed by evaporation to give 4-dimethylcarbamoyloxy-2,5-dimethylphenyl methyl sulphide, boiling point 146° C. at 0.6 mm to 150° C. to 0.9 mm.

출처