반응 #555221

반응 방정식

acetic acid

L-cysteine hydrochloride

ethyl bromide

Ammonia water

→

desired product

S-ethyl-L-cysteine

용매

water

water

반응 조건

후처리

1. 1
   기타is formed
2. 2
   workup.ADDITIONto further dilute the mixture
3. 3
   기타After 2 hours reaction

실험 절차

SEC is synthesized from L-cysteine hydrochloride (1.58 g, 0.01 mol) and ethyl bromide (1.09 g, 0.01 mol) with the following steps. The reaction mixture is diluted with water in a titration manner until a clear solution is formed. No more than necessary amount of water should be added to further dilute the mixture. Ammonia water was added to PH 9.5-10 with stirring at room temperature. After 2 hours reaction, the mixture is acidified with acetic acid to PH 5-5.5. The desired product was cooled in the refrigerator, filtered and washed successively with water and ethyl ether. The chemical structure of SEC is determined by Proton Nuclear Magnetic Resonance Spectroscopy.

출처