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3,3-dimethyl-pyrrolidine

4-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester

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title compound

수율 20.0%

6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carboxylic acid [3-(3,3-dimethyl-pyrrolidine-1-carbonyl)-1-methyl-1H-pyrazol-4-yl]-amide

수율 20.0%

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실험 절차

According to the general method described in step 5 of example 27, reaction of 3,3-dimethyl-pyrrolidine with 4-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-1-methyl-1H-pyrazole-3-carboxylic acid methyl ester provided the title compound (20%) as amorphous yellow solid.

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