반응 #554599

반응 방정식

boron boron tribromide

water

2-methoxytriphenylene

→

2-hydroxytriphenylene

수율 95.1%

용매

methylene chloride

methylene chloride

반응 조건

후처리

1. 1
   온도while increasing temperature of the reaction solution to room temperature
2. 2
   여과followed by filtration
3. 3
   세척The resulting solid was washed with water and methanol

실험 절차

Under an argon atmosphere, 13.9 g of 2-methoxytriphenylene was placed in a flask, and 300 mL of methylene chloride was added. The reaction solution was cooled to −78° C., and 54 mL of a solution of 1M boron boron tribromide in methylene chloride was dropwise added thereto. The reaction solution was stirred for 5 hours while increasing temperature of the reaction solution to room temperature. 100 mL of water was added to the reaction solution, followed by filtration. The resulting solid was washed with water and methanol to obtain 12.5 g (yield: 95%) of 2-hydroxytriphenylene.

출처