반응 #554567

반응 방정식

Phosphorus oxychloride

dimethylaniline

phenanthridine

→

9-chlorophenanthridine

수율 96.0%

용매

H2O

반응 조건

후처리

1. 1
   온도by refluxing for 3 hours
2. 2
   추출the obtained solid was extracted with chloroform
3. 3
   건조by drying with sodium sulfate
4. 4
   여과After filtration
5. 5
   기타the filtrate was evaporated to dryness under reduced pressure
6. 6
   기타The obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%)

실험 절차

Phosphorus oxychloride (15 ml) and dimethylaniline (0.63 ml) were added to phenanthridine (2.0 g), followed by refluxing for 3 hours. The solution was poured into H2O to generate a solid, and the obtained solid was extracted with chloroform, followed by drying with sodium sulfate. After filtration, the filtrate was evaporated to dryness under reduced pressure. The obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%).

출처