반응 #55271

ord-1b94e2ca83704bf18a638326993a2758

반응 방정식

CC#C[C@@H](C[C@H](C)CCCC(C)C)OC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1
6(R),10-dimethyl-undecan-2-yn-4(R)-ol 3,5-dinitrobenzoate
[Na+].[OH-]
NaOH
→
CC#C[C@H](O)C[C@H](C)CCCC(C)C
6(R),10-dimethyl-undecan-2-yn-4(R)-ol
수율 98.8%

반응물

CC#C[C@@H](C[C@H](C)CCCC(C)C)OC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1
6(R),10-dimethyl-undecan-2-yn-4(R)-ol 3,5-dinitrobenzoate
[Na+].[OH-]
NaOH

시약

없음

용매

CO
methanol

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

6.65 g (0.0171 mol) of 6(R),10-dimethyl-undecan-2-yn-4(R)-ol 3,5-dinitrobenzoate and 35 ml of 6 N aqueous NaOH in methanol (300 ml) were refluxed for 11/2 hr. It was worked up as in Example 45 to give 3.30 g (98.8%) of pure 6(R),10-dimethyl-undecan-2-yn-4(R)-ol as a colorless oil.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04151360uspto-grants-1979_04