반응 #55270

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6(R),10-dimethyl-undecan-2-yn-4(R)-ol

3,5-dinitrobenzoic acid

p-toluenesulfonyl chloride

→

6(R),10-Dimethyl-undecan-2-yn-4(R)-ol 3,5-dinitrobenzoate

용매

pyridine

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후처리

1. 1
   기타This compound was prepared similar to the method
2. 2
   기타2 hr
3. 3
   기타to give
4. 4
   기타after recrystallization once from methanol 6.73 g (84.2%) of pure 6(R),10-dimethyl-undecan-2-yn-4(R)-ol 3,5-dinitrobenzoate, m.p. 90°-91°

실험 절차

This compound was prepared similar to the method described in Example 44 from 4.22 g (21.6 mmol) of 6(R),10-dimethyl-undecan-2-yn-4(R)-ol, 4.58 g (21.6 mmol) of 3,5-dinitrobenzoic acid and 8.25 g (43.2 mmol) of p-toluenesulfonyl chloride in dry pyridine (total 55 ml) at 4° C. for 31/2 hr. It was worked up as described in Example 44 to give after recrystallization once from methanol 6.73 g (84.2%) of pure 6(R),10-dimethyl-undecan-2-yn-4(R)-ol 3,5-dinitrobenzoate, m.p. 90°-91°.

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