반응 #55268

반응 방정식

3(R),7-dimethyl octanoic acid ethyl ester

methanol

→

R-(+)-dihydrocitronellic acid

수율 87.5%

3(R),7-dimethyloctanoic acid

수율 87.5%

용매

NaOH

반응 조건

후처리

1. 1
   기타to give 226 mg

실험 절차

300 mg. of 3(R),7-dimethyl octanoic acid ethyl ester obtained from example 14 was refluxed in 6 N NaOH (1 ml.), methanol (4 ml.) for 2 hours. It was worked up as in Example 10 to give 226 mg. (87.5% yield) of R-(+)-dihydrocitronellic acid, b.p. 54°/0.4 mmHg. (Kugelrohr), [α]D25 +6.31° (c=5.069, CHCl3).

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