반응 #55214

ord-1d54763d22894a2c88ead86dcea40063

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도under reflux for 2 hours

실험 절차

3.20 g. of 3-acetoxy-3 -(2',4'-difluoro-4-biphenylyl)butan-1-ol and 2 g. of KOH in 50 ml. of methanol are heated under reflux for 2 hours. Water and chloroform are added and the reaction mixture is worked up to give 3-(2',4'-difluoro-4-biphenylyl)butane-1,3-diol, m.p. 82°-84°.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04151302uspto-grants-1979_04