반응 #55211

반응 방정식

3-(2',4'-difluoro-4-biphenylyl)butyramide

hydrochloric acid

acetic acid

→

3-(2' ,4'-difluoro-4-biphenylyl)butyric acid

용매

water

반응 조건

후처리

1. 1
   workup.ADDITIONA mixture of 1 g
2. 2
   온도under reflux for 48 hours

실험 절차

A mixture of 1 g. of 3-(2',4'-difluoro-4-biphenylyl)butyramide, 2 ml. of concentrated hydrochloric acid and 2 ml. of acetic acid is heated under reflux for 48 hours and, after addition of water, is worked up in the customary manner to give 3-(2' ,4'-difluoro-4-biphenylyl)butyric acid, m.p. 109°-110°.

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