반응 #551999

반응 방정식

3-aminoindazole

phthalic acid

diethyl ether

→

3-phthalimidoindazole

수율 87.0%

용매

water

반응 조건

후처리

1. 1
   workup.ADDITIONwas added
2. 2
   workup.STIRRINGthe mixture was stirred
3. 3
   기타to separate crystals
4. 4
   기타The crystals were obtained by filtration
5. 5
   기타dried under reduced pressure

실험 절차

5.0 g of the same 3-aminoindazole as Example 1 and 6.68 g of phthalic acid were added to 50 ml of dixoane, and the mixture was stirred for 5 hours at 120° C. The mixture was condensed under reduced pressure, 30 ml of diethyl ether was added and the mixture was stirred under cooling with ice and water for 30 minutes to separate crystals. The crystals were obtained by filtration and dried under reduced pressure to give 8.6 g of 3-phthalimidoindazole in a yield of 87%.

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