반응 #55193

반응 방정식

3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid

→

3-(2',4'-difluoro-4-biphenylyl)butyric acid

용매

acetic acid

반응 조건

후처리

1. 1
   기타is hydrogenated, at 20° and under normal pressure, on 0.2 g
2. 2
   여과The mixture is filtered
3. 3
   workup.ADDITIONthe filtrate is diluted with water

실험 절차

A solution of 3.18 g. of 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid in 30 ml. of acetic acid is hydrogenated, at 20° and under normal pressure, on 0.2 g. of 10% Pd/C in the presence of 0.01 ml. of HClO4. The mixture is filtered and the filtrate is diluted with water to give 3-(2',4'-difluoro-4-biphenylyl)butyric acid, m.p. 109°-110°.

출처