반응 #55178

ord-6ea46449299644f789be9b85c5d1d17c

용매

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    온도under reflux with 2 g
  2. 2
    기타evaporated

실험 절차

10 g. of 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid ethyl ester are dissolved in 50 ml. of ethanol and the solution is heated under reflux with 2 g. of KOH for 3 hours, evaporated and worked up in the customary manner to give 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid, m.p. 121°-123°.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04151302uspto-grants-1979_04