반응 #54985

반응 방정식

2-chloro-5-trifluoromethyl-aniline

ethoxymethylenemalononitrile

→

N-(2,2-dicyanovinyl)-2-chloro-5-trifluoromethylaniline

수율 70.0%

용매

ethanol

반응 조건

후처리

1. 1
   온도the mixture is refluxed for 48 hours
2. 2
   온도After cooling
3. 3
   여과the precipitated product is collected by filtration
4. 4
   세척washed with ethanol
5. 5
   기타Recrystallisation from ethanol
6. 6
   기타affords the above product with a melting point of 166°-169° C.

실험 절차

19.6 Parts of 2-chloro-5-trifluoromethyl-aniline and 12.2 parts of ethoxymethylenemalononitrile are dissolved in 125 parts of ethanol and the mixture is refluxed for 48 hours. After cooling, the precipitated product is collected by filtration and washed with ethanol. Recrystallisation from ethanol affords the above product with a melting point of 166°-169° C. and in a 70% yield.

출처