반응 #54891

반응 방정식

4-(4-acetyl-8-hydroxytridecyl)benzoic acid

acetic anhydride

→

crude product

4-(4-Acetyl-8-acetoxytridecyl)benzoic Acid

용매

ethyl ether

반응 조건

후처리

1. 1
   온도The mixture is then cooled
2. 2
   workup.DISSOLUTIONdissolved in 80 ml
3. 3
   추출The solution is extracted with an ice-cold solution of 8 g
4. 4
   기타The basic solution is separated
5. 5
   세척washed with water
6. 6
   건조dried over sodium sulfate
7. 7
   기타The ether is evaporated

실험 절차

A mixture of 4-(4-acetyl-8-hydroxytridecyl)benzoic acid (9.0 g., 0.025 mole) and acetic anhydride (6.1 g., 0.06 mole) is heated at 60° C. for 18 hours. The mixture is then cooled and dissolved in 80 ml. ethyl ether. The solution is extracted with an ice-cold solution of 8 g. sodium hydroxide in 150 ml. water. The basic solution is separated and acidified with concentrated hydrochloric acid. The oily acid which separates is taken up in ether, washed with water, and dried over sodium sulfate. The ether is evaporated to leave the oily crude product.

출처