반응 #54889
ord-2c63af5457b94fa0bd77f1f3794a6fa2
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타to destroy the excess diazomethane
- 2세척the solution is washed with dilute sodium bicarbonate solution and water
- 3건조dried over sodium sulfate
- 4기타Evaporation of volatile materials at reduced pressure
실험 절차
A solution of diazomethane (approximately 2.5 g., 0.06 mole) in ether (100 ml.) is mixed with a solution of 4-(4-acetyl-8-hydroxytridecyl)benzoic acid (10.8 g., 0.03 mole) in ether (50 ml.). The resulting solution is allowed to stand 4 hours at room temperature. Acetic acid is then added to destroy the excess diazomethane and the solution is washed with dilute sodium bicarbonate solution and water and dried over sodium sulfate. Evaporation of volatile materials at reduced pressure yields methyl 4-(4-acetyl-8-hydroxytridecyl)benzoate, a colorless viscous oil.