반응 #54746

반응 방정식

2-aminobenzothiazole

diethyl oxalate

→

desired product

수율 44.0%

Ethyl (2-Benzothiazolyl)Oxamate

수율 44.0%

반응 조건

후처리

1. 1
   온도is heated
2. 2
   온도at reflux for 2.5 hours
3. 3
   기타A white solid precipitates from the cooled reaction mixture
4. 4
   기타The solid is recrystallized from ethanol (
5. 5
   여과with a hot filtration)

실험 절차

A mixture of 2-aminobenzothiazole (5.0 g., 0.033 mol) and diethyl oxalate (50 ml.) is heated at reflux for 2.5 hours. A white solid precipitates from the cooled reaction mixture. The solid is recrystallized from ethanol (with a hot filtration) to give the desired product (3.72 g., m.p. 185°-186°, 44%).

출처