반응 #54642

반응 방정식

trichlorobenzene

8-chloro-5-amino-quinaldine

phthalic anhydride

→

8-chloro-5-phthalimidoquinaldine

수율 83.3%

반응 조건

후처리

1. 1
   기타the mixture was reacted
2. 2
   온도under reflux for 2 hours at the boiling point
3. 3
   온도After cooling
4. 4
   기타the precipitated crystals were separated by filtration
5. 5
   기타dried

실험 절차

95 g of trichlorobenzene was added to 23.3 g (0.12 mole) of 8-chloro-5-amino-quinaldine and 18.0 g (0.12 mole) of phthalic anhydride, and the mixture was reacted under reflux for 2 hours at the boiling point. After cooling, the precipitated crystals were separated by filtration, and dried to afford 32 g (0.10 mole) of 8-chloro-5-phthalimidoquinaldine.

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