반응 #54594
ord-6e1284b316994e4b8f3c00440d36aaba
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1온도The solution is heated
- 2온도to reflux for 5 minutes
- 3온도refluxed for an additional 2 minutes
- 4기타evaporated
- 5기타leaving a residue which
- 6여과The ethyl acetate is filtered
- 7기타dried
- 8기타evaporated
실험 절차
To a solution of sodium acetate (0.1 mole) in about 300 ml of glacial acetic acid is added about 0.05 mole of α-sulfo-α-aminoacetic acid hydrochloride. The solution is heated to reflux for 5 minutes, 2,5-dimethoxytetrahydrofuran (1 equivalent based on α-sulfo-α-aminoacetic acid hydrochloride) is added as quickly as possible, and the solution refluxed for an additional 2 minutes. The acetic acid is flash evaporated leaving a residue which is taken up in ethylacetate. The ethyl acetate is filtered, dried and evaporated to give α-sulfo-α-(1-pyrryl) acetic acid.