반응 #545450

반응 방정식

DMF

4-amino-2-hydroxybenzene sulfonic acid

2,3,5,6-tetrafluoro-4-trifluoromethylbenzyl bromide

→

2-hydroxy-5-(2,3,5,6-tetrafluoro-4-trifluoromethylbenzylamino)benzene sulfonic acid

수율 28.0%

반응 조건

후처리

1. 1
   기타According to the similar procedure in Synthesis Example 1

실험 절차

According to the similar procedure in Synthesis Example 1, by using 4-amino-2-hydroxybenzene sulfonic acid (1.00 g, 5.30 mmole), DMF (10 ml), TEA (1.0 ml), and 2,3,5,6-tetrafluoro-4-trifluoromethylbenzyl bromide (0.88 g, 5.30 mmole), 0.61 g (28.0% yield) of 2-hydroxy-5-(2,3,5,6-tetrafluoro-4-trifluoromethylbenzylamino)benzene sulfonic acid was obtained as a yellow solid.

출처