반응 #54523

반응 방정식

phenoxy acetyl chloride

N,N-diethylethylene diamine

pyridine

→

desired product

수율 66.3%

N-(2'-DIETHYLAMINOETHYL)PHENOXYACETAMIDE

수율 66.3%

용매

methylene chloride

반응 조건

후처리

1. 1
   기타to rise to 0° C
2. 2
   세척The reaction mixture was then washed with a 200 milliliter portion of water

실험 절차

First, 20 milliliters (0.05 mole) N,N-diethylethylene diamine, 50 milliliters methylene chloride, and 5.2 milliliters (0.065 mole) pyridine were combined in a flask. Next, 10.24 grams (0.06 mole) phenoxy acetyl chloride was added at -60° C. with stirring. The temperature was allowed to rise to 0° C. The reaction mixture was then washed with a 200 milliliter portion of water and a 100 milliliter portion of saturated sodium carbonate solution. The organic solution was stripped in vacuum to yield 8.3 grams of the desired product. nD30 1.5118.

출처