반응 #543553

반응 방정식

Phenylalanine methyl ester

Cyclohexanoyl chloride

→

N-cyclohexanoylphenylalanine methyl ester

용매

pyridine

반응 조건

후처리

1. 1
   workup.ADDITIONThe reaction mixture is poured onto hydrochloric acid (1N)
2. 2
   기타crushed ice
3. 3
   추출The aqueous mixture is extracted twice with toluene
4. 4
   농축The combined toluene extracts are concentrated in vacuo

실험 절차

Phenylalanine methyl ester (1 g., 0.0046 moles) is dissolved in pyridine 5 mL. Cyclohexanoyl chloride (0.62 mL) is added and the mixture is stirred for 2 hours. The reaction mixture is poured onto hydrochloric acid (1N) and crushed ice. The aqueous mixture is extracted twice with toluene. The combined toluene extracts are concentrated in vacuo to give 1.1 g of crude N-cyclohexanoylphenylalanine methyl ester.

출처