반응 #5435

반응 방정식

4-bromophenol

3-tributylstannylpyridine

→

above compound

수율 60.0%

4-(3-pyridyl)-phenol

수율 60.0%

용매

dioxane

반응 조건

후처리

1. 1
   온도refluxed for 15 hours
2. 2
   농축After concentration
3. 3
   기타by evaporation
4. 4
   기타in a vacuum and purification on silica gel

실험 절차

26.8 g of 4-bromophenol was taken under protective gas in 1000 ml of dioxane, mixed with 90 g 3-tributylstannylpyridine [preparation according to litt.: Org. Magn. Resonance, 7 (1975), 610] and 11.1 g of bis-(triphenylphosphine)-palladium(II) chloride and refluxed for 15 hours. After concentration by evaporation in a vacuum and purification on silica gel, 15.92 g of the above compound is isolated.

출처