반응 #54297

반응 방정식

2,6-dimethylaniline

butyryl chloride

→

N-butyryl-2,6-dimethylaniline

용매

ether

ether

반응 조건

후처리

1. 1
   기타15 hours
2. 2
   기타at room temperature
3. 3
   기타The reaction mixture is then evaporated in vacuo
4. 4
   여과of water, filtered
5. 5
   세척washed with water
6. 6
   기타dried

실험 절차

A solution of 200 g. of 2,6-dimethylaniline in 2 l. of ether is cooled in an ice bath and to this 88 g. of butyryl chloride in 150 ml. of ether is added dropwise (over 21/2 hours). A white precipitate forms and the reaction mixture is allowed to stir at 0° C. for 1 hour longer and then 15 hours at room temperature. The reaction mixture is then evaporated in vacuo and the white solid residue is slurried in 1 l. of water, filtered and washed with water and dried to obtain N-butyryl-2,6-dimethylaniline (m.p. 134°-6° C.).

출처