반응 #54289

반응 방정식

3-(4-chlorobenzoyl)-benzeneacetic acid

thionyl chloride

→

3-(4-chlorobenzoyl)-benzeneacetic acid chloride

반응 조건

후처리

1. 1
   온도to reflux
2. 2
   기타excess thionyl chloride was removed under reduced pressure
3. 3
   workup.DISSOLUTIONThe residue was dissolved in benzene
4. 4
   기타the solution was evaporated to dryness under reduced pressure
5. 5
   workup.DISSOLUTIONThe residue was dissolved in 50ml of anhydrous benzene

실험 절차

A solution of 8.235 g of 3-(4-chlorobenzoyl)-benzeneacetic acid in 20 ml of thionyl chloride was heated to reflux and then excess thionyl chloride was removed under reduced pressure. The residue was dissolved in benzene and the solution was evaporated to dryness under reduced pressure. The residue was dissolved in 50ml of anhydrous benzene to obtain a solution of 3-(4-chlorobenzoyl)-benzeneacetic acid chloride which was used as is for the next step.

출처