반응 #54241

반응 방정식

cyclohexa(b)furan-4-one

potassium cyanide

ammonium carbonate

water

hydrochloric acid

→

spiro[cyclohexa(b)furan-4,4'-imidazolidine]-2', 5'-dione

용매

ethanol

반응 조건

후처리

1. 1
   온도The reaction mixture was cooled
2. 2
   기타The precipitated product was isolated by filtration
3. 3
   기타recrystallized from ethanol

실험 절차

A mixture of 2.7 g of cyclohexa(b)furan-4-one (Bull. Soc. Chim. Fr., 1967, 2796), 1.95 g of potassium cyanide and 9.6 g of powdered ammonium carbonate were heated with 40 ml of 95% aqueous ethanol at 110°-120° C. in a steel bomb for 16 hours. The reaction mixture was cooled, diluted with 200 ml of water, and acidified with 12 N hydrochloric acid. The precipitated product was isolated by filtration and recrystallized from ethanol to give 1.73 g of spiro[cyclohexa(b)furan-4,4'-imidazolidine]-2', 5'-dione, mp 245°-248° C.

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