반응 #54238

반응 방정식

2-Bromo-3-phenyl-butyrophenone

1,2,4-triazole

potassium carbonate

→

title compound

2-(1,2,4-Triazol-1-yl)-3-phenylbutyrophenone

용매

methyl ethyl ketone

반응 조건

후처리

1. 1
   여과the solution was filtered
2. 2
   기타the solvent removed in vacuo
3. 3
   기타Recrystallisation of the residue from ethanol/petroleum ether (60°-80°)

실험 절차

2-Bromo-3-phenyl-butyrophenone (0.02 mol), 1,2,4-triazole (0.02 mol) and potassium carbonate (0.04 mol) were refluxed in methyl ethyl ketone (100 ml) for 36 hours. After cooling to room temperature, the solution was filtered and the solvent removed in vacuo. Recrystallisation of the residue from ethanol/petroleum ether (60°-80°) gave the title compound as a colourless solid, m.p. 166°-8°.

출처