반응 #54164

반응 방정식

carbinol

1-(3,3-dimethyl-cyclohex-1-en-1-yl)-pent-4-en-1-yne

→

1-(3,3-dimethyl-cyclohex-6-en-1-yl)-pent-4-en-1-yne

수율 70.0%

용매

water

반응 조건

후처리

1. 1
   온도The temperature was then slowly increased to 120°-130°

실험 절차

(c') 7 g of the above prepared carbinol were heated in a distillation apparatus in the presence of 2 g of H3BO3 at 12 Torr until no further formation of water was observed. The temperature was then slowly increased to 120°-130° and a 2:3 mixture of 1-(3,3-dimethyl-cyclohex-1-en-1-yl)-pent-4-en-1-yne and 1-(3,3-dimethyl-cyclohex-6-en-1-yl)-pent-4-en-1-yne was obtained (5.3 g; 70% yield). The subsequent conversion to the desired cyclohexenic ketones is effected according to the procedure given above (pathway I) paragraph d)

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