반응 #54153

반응 방정식

4-diethylaminosalicylaldehyde

dimethyl 1,3-acetone dicarboxylate

→

methyl 7-diethylamino-3coumarinoylacetate

반응 조건

후처리

1. 1
   온도under reflux on a steam bath for 2 hours
2. 2
   온도After chilling in the freezer
3. 3
   기타the product was collected
4. 4
   기타recrystallized from a mixture of alcohol and acetonitrile

실험 절차

A solution of 1.93 g 4-diethylaminosalicylaldehyde, 1.80 g. dimethyl 1,3-acetone dicarboxylate in 10 ml. alcohol containing 10 drops piperidine was heated under reflux on a steam bath for 2 hours. After chilling in the freezer, the product was collected and recrystallized from a mixture of alcohol and acetonitrile. Yield 2.6 g (82%).

출처