반응 #54151

반응 방정식

2-hydroxy-4-methoxybenzaldehyde

ethyl acetoacetate

→

3-acetyl-7-methoxycoumarin

반응 조건

후처리

1. 1
   온도was warmed on a hot plate until solution
2. 2
   온도to be heated gently
3. 3
   workup.WAITAfter several minutes the reaction mixture solidified
4. 4
   온도After cooling
5. 5
   기타the product was recrystallized from a mixture of alcohol and acetonitrile

실험 절차

A mixture of 15.2 g 2-hydroxy-4-methoxybenzaldehyde and 13.5 g ethyl acetoacetate was warmed on a hot plate until solution was attained. Thirty drops of piperidine were added and the reaction mixture continued to be heated gently. After several minutes the reaction mixture solidified. After cooling, the product was recrystallized from a mixture of alcohol and acetonitrile. Yield 20 g.

출처