반응 #54149

반응 방정식

2-(4-hydroxy-1-naphthoxy)propionic acid

potassium dihydrogen phosphate

potassium nitrosodisulfonate

→

4-(1-Carboxyethoxy)-1,2-naphthoquinone

용매

ethanol

water

반응 조건

후처리

1. 1
   기타The yellow-brown solid was collected
2. 2
   세척washed with a litter water
3. 3
   기타dried (under nitrogen)

실험 절차

To a solution of 38.0 g potassium dihydrogen phosphate in 7.5 l of distilled water (pH 4.0) was added 89.4 g (0.33 mol) potassium nitrosodisulfonate (Fremy's reagent). To this solution was added immediately a solution of 34.8 g (0.15 mol) of 2-(4-hydroxy-1-naphthoxy)propionic acid in 125 ml ethanol. The mixture was stirred for 2.5 hours under nitrogen at room temperature. The yellow-brown solid was collected, washed with a litter water and dried (under nitrogen). The yield was 30.0 g (81 percent). The crude product melted at 182° to 184° C.

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