반응 #53908
ord-87ca8e65c17446c9b2bcadba7e18d7f8
반응 방정식
methyl-propyl-amine
trans-Methanesulfonic acid 4-(4-methylamino-cyclohexyl)-butyl ester
trifluoro-acetic acid
4-trifluoromethyl-phenyl-sulfonylchloride
→
trans-N-Methyl-N-{4-[4-(methyl-propyl-amino)-butyl]-cyclohexyl}-4-trifluoromethyl-benzenesulfonamide
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
In analogy to examples 31.5 and 31.6, trans-Methanesulfonic acid 4-(4-methylamino-cyclohexyl)-butyl ester.trifluoro-acetic acid and 4-trifluoromethyl-phenyl-sulfonylchloride were reacted, followed by treatment with methyl-propyl-amine to give trans-N-Methyl-N-{4-[4-(methyl-propyl-amino)-butyl]-cyclohexyl}-4-trifluoromethyl-benzenesulfonamide, MS: 449 (MH+).