반응 #53892
ord-807a9fec619941e58097b08948ea1137
반응 방정식
2-(2-Hydroxy-ethylamino)-ethanol
trans-Methansulfonic acid 5-(4-methyl amino-cyclohexyl)-pentyl ester
trifluoroacetic acid
4-trifluoromethyl-phenyl sulfonylchloride
→
trans-N-(4-{5-[Bis-(2-hydroxy-ethyl)-amino]-pentyl}-cyclohexyl)-N-methyl-4-trifluoromethyl-benzenesulfonamide
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
In analogy to examples 29.10 and 29.11, trans-Methansulfonic acid 5-(4-methyl amino-cyclohexyl)-pentyl ester.trifluoroacetic acid salt and 4-trifluoromethyl-phenyl sulfonylchloride were reacted) followed by treatment with 2-(2-Hydroxy-ethylamino)-ethanol to give trans-N-(4-{5-[Bis-(2-hydroxy-ethyl)-amino]-pentyl}-cyclohexyl)-N-methyl-4-trifluoromethyl-benzenesulfonamide. MS: 495 (MH+).