반응 #53882
ord-efb5a997550142f4b024f995dd4838b7
반응 방정식
2-ethylamino-ethanol
trans-Methansulfonic acid 5-(4-methyl amino-cyclohexyl)-pentyl ester
trifluoroacetic acid
4-(trifluoromethyl)benzenesulphonyl chloride
→
trans-N-(4-{5-[Ethyl-(2-hydroxy-ethyl)-amino]-pentyl}-cyclohexyl)-N-methyl-4-trifluoromethyl-benzenesulfonamide
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
In analogy to examples 29.10 and 29.11, trans-Methansulfonic acid 5-(4-methyl amino-cyclohexyl)-pentyl ester.trifluoroacetic acid salt and 4-(trifluoromethyl)benzenesulphonyl chloride were reacted, followed by treatment with 2-ethylamino-ethanol to yield trans-N-(4-{5-[Ethyl-(2-hydroxy-ethyl)-amino]-pentyl}-cyclohexyl)-N-methyl-4-trifluoromethyl-benzenesulfonamide, MS: 479 (MH+).