반응 #53530

ord-0c47788f338948049fec5c8f44ca55d6

반응 방정식

N=C1NC(=O)c2ccccc21
3-imino-2,3-dihydro-isoindol-1-one
CCCN1CCC(C#N)(NC(=O)C(N)CC(C)(C)C)CC1.Cl.Cl
2-amino-4,4-dimethyl-pentanoic acid (4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt
→
CCCN1CCC(C#N)(NC(=O)C(CC(C)(C)C)NC2=NC(=O)c3ccccc32)CC1
title compound
CCCN1CCC(C#N)(NC(=O)C(CC(C)(C)C)NC2=NC(=O)c3ccccc32)CC1
4,4-Dimethyl-2-(3-oxo-3H-isoindol-1-ylamino)-pentanoicacid-(4-cyano-1-propyl-piperidin-4-yl)-amide

반응물

N=C1NC(=O)c2ccccc21
3-imino-2,3-dihydro-isoindol-1-one
CCCN1CCC(C#N)(NC(=O)C(N)CC(C)(C)C)CC1.Cl.Cl
2-amino-4,4-dimethyl-pentanoic acid (4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared from 3-imino-2,3-dihydro-isoindol-1-one and 2-amino-4,4-dimethyl-pentanoic acid (4-cyano-1-propyl-piperidin-4-yl)amide bis hydrochloride salt according to the procedure from Example 15. MS, m/z 424.5=M+1.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06858623B2uspto-grants-2005_02