반응 #53257

반응 방정식

p-toluenesulfonylisocyanate

n-butyl 3-aminobenzoate

n-butyl 3-aminobenzoate

→

butyl 3-(p-toluenesul-fonylamino carbonylamino)benzoate

용매

toluene

반응 조건

후처리

1. 1
   기타In a three-necked flask equipped with a dropping funnel
2. 2
   workup.STIRRINGContinuous stirring of the reaction mixture
3. 3
   기타an exothermic reaction
4. 4
   기타precipitating a large amount of white solid

실험 절차

In a three-necked flask equipped with a dropping funnel, a thermometer and a reflux condenser 15.4 g of n-butyl 3-aminobenzoate was placed and 150 ml of toluene was added thereto with stirring to dissolve n-butyl 3-aminobenzoate therein. With stirring the resultant mixture by a magnetic stirrer, 17.3 g of p-toluenesulfonylisocyanate was added dropwise to the mixture through the dropping funnel at room temperature. Continuous stirring of the reaction mixture caused an exothermic reaction, thereby precipitating a large amount of white solid.

출처