반응 #53219

ord-cc02e279fcfa414bbc246d711233f1de

반응 방정식

CC(C)S(=O)(=O)Nc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1
(Z)-3-{1-[4-(isopropylsulphonylamino)-phenylamino]-1-phenyl-methylidene}-2-indolinone
CN(C)CCCl
1-chloro-2-dimethylamino-ethane
O=C([O-])[O-].[K+].[K+]
potassium carbonate
[I-].[Na+]
sodium iodide
→
CC(C)S(=O)(=O)N(CCN(C)C)c1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1
(Z)-3-{1-[4-(N-(2-dimethylaminoethyl)-N-isopropylsulphonyl-amino]-phenylamino]-1-phenyl-methylidene}-2-indolinone

반응물

CC(C)S(=O)(=O)Nc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1
(Z)-3-{1-[4-(isopropylsulphonylamino)-phenylamino]-1-phenyl-methylidene}-2-indolinone
CN(C)CCCl
1-chloro-2-dimethylamino-ethane
O=C([O-])[O-].[K+].[K+]
potassium carbonate
[I-].[Na+]
sodium iodide

시약

없음

용매

CC(C)=O
acetone

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Prepared analogously to Example 36 from (Z)-3-{1-[4-(isopropylsulphonylamino)-phenylamino]-1-phenyl-methylidene}-2-indolinone, 1-chloro-2-dimethylamino-ethane, potassium carbonate and sodium iodide in acetone.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06855710B2uspto-grants-2005_02