반응 #53194

ord-4bb65f27294d48a2903d32dd2df8651a

반응 방정식

CC(=O)N1C(=O)C(=C(Cl)c2cccc(Cl)c2)c2cc([N+](=O)[O-])ccc21
1-acetyl-3-[1-chloro-1-(3-chlorophenyl)-methylidene)-5-nitro-2-indolinone
CN(C)Cc1ccc(N)cc1
4-dimethylaminomethyl-aniline
[Na+].[OH-]
sodium hydroxide
→
CN(C)Cc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2cccc(Cl)c2)cc1
(Z)-3-[1-(4-dimethylaminomethyl-phenylamino)-1-(3-chlorophenyl)-methylidene]-5-nitro-2-indolinone

반응물

CC(=O)N1C(=O)C(=C(Cl)c2cccc(Cl)c2)c2cc([N+](=O)[O-])ccc21
1-acetyl-3-[1-chloro-1-(3-chlorophenyl)-methylidene)-5-nitro-2-indolinone
CN(C)Cc1ccc(N)cc1
4-dimethylaminomethyl-aniline
[Na+].[OH-]
sodium hydroxide

시약

없음

용매

CN(C)C=O
DMF
CO
methanol

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Prepared analogously to Example 2 from 1-acetyl-3-[1-chloro-1-(3-chlorophenyl)-methylidene)-5-nitro-2-indolinone and 4-dimethylaminomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06855710B2uspto-grants-2005_02