반응 #53183

ord-80a85c0e0a0a412982f8beabced7b0eb

반응 방정식

CC(=O)N1C(=O)C(=C(Cl)c2cccc(C)c2)c2ccccc21
1-acetyl-3-[1-chloro-1-(m-tolyl)-methylidene)-2-indolinone
CN(C)Cc1ccc(N)cc1
4-dimethylaminomethyl-aniline
[Na+].[OH-]
sodium hydroxide
→
Cc1cccc(/C(Nc2ccc(CN(C)C)cc2)=C2/C(=O)Nc3ccccc32)c1
(Z)-3-[1-(4-dimethylaminomethyl-phenylamino)-1-(m-tolyl)-methylidene]-2-indolinone

반응물

CC(=O)N1C(=O)C(=C(Cl)c2cccc(C)c2)c2ccccc21
1-acetyl-3-[1-chloro-1-(m-tolyl)-methylidene)-2-indolinone
CN(C)Cc1ccc(N)cc1
4-dimethylaminomethyl-aniline
[Na+].[OH-]
sodium hydroxide

시약

없음

용매

CN(C)C=O
DMF
CO
methanol

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Prepared analogously to Example 2 from 1-acetyl-3-[1-chloro-1-(m-tolyl)-methylidene)-2-indolinone and 4-dimethylaminomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06855710B2uspto-grants-2005_02