반응 #531803

반응 방정식

4c

N-(Tris(3-benzyloxy-4-oxo-4H-pyran-2-yl)carboxyaminopropyl)methyl benzamide

→

title compound 6

수율 114.7%

N-(Tris(-3-hydroxy-4-oxo-4H-pyran-2-yl)carboxyaminopropyl)methyl benzamide

수율 114.7%

용매

acetic acid

hydrochloric acid

반응 조건

후처리

1. 1
   농축The reaction mixture was concentrated in vacuo
2. 2
   기타the residue azeotroped several times with methanol (10 ml)

실험 절차

A solution of 4c (0.20 g, 0.20 mmol) in glacial acetic acid (2 ml) and concentrated hydrochloric acid (2 ml) was stirred at room temperature for 18 h. The reaction mixture was concentrated in vacuo, the residue azeotroped several times with methanol (10 ml) to afford the title compound 6 (130 mg, 90%) as a red-orange solid.

출처