반응 #531429

반응 방정식

methyl undecyl ketone

formamide

→

2-formamidotridecane

용매

formic acid

반응 조건

후처리

1. 1
   온도The reaction mixture is cooled
2. 2
   workup.ADDITIONpoured on ice
3. 3
   추출extracted with ether
4. 4
   추출the ethereal extract
5. 5
   건조is dried over Na2SO4
6. 6
   workup.DISTILLATIONAfter distilling off the ether
7. 7
   workup.DISTILLATIONthe oily residue is distilled in vacuo

실험 절차

70 g of methyl undecyl ketone are added to 250 ml of formamide. The mixture is heated, with constant stirring, to 160° C. Then 40 ml of formic acid are added dropwise in the course of 24 hours. The reaction mixture is cooled, poured on ice, extracted with ether and the ethereal extract is dried over Na2SO4. After distilling off the ether, the oily residue is distilled in vacuo, affording 60 g of 2-formamidotridecane. Boiling point: 145°-155° C./0.01.

출처